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BIOGRAPHICAL SKETCH

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NAME: TieJun Huang

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POSITION TITLE: Professor

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EDUCATION/TRAINING

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A.Personal statement

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Tiejun Huang is a Chief Physician, doctor and postgraduate tutor who is primarily interested in the use of nuclear medicine for diagnosis and treatment. He is the Chairman of the Nuclear Medicine Professional Committee of the Shenzhen branch of the Chinese Medical Association, a standing committee member of the Nuclear Medicine Professional Committee of the Guangdong branch of the Chinese Medical Association, and a member of the Nuclear Medicine Branch of the Chinese Medical Association.

His work is supported by the Scientific Research Fund of the Shenzhen Science and Innovation commission, with grants totalling 230,000 yuan. He has published high-level academic papers in Cancer Management and Research, Oncogene, Cell Death and Disease and in other international journals as the first author.

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B. Positions and honors

Positions

Chairman of the Nuclear Medicine Professional Committee of the Shenzhen Branch of the Chinese Medical Association

Standing Committee Member of the Nuclear Medicine Professional Committee of the Guangdong Branch of the Chinese Medical Association

Member of the Nuclear Medicine Branch of the Chinese Medical Association

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C. Representative publications (selected publications in recent five years)

1.H-F Xu, T-J Huang et al.?Candidate tumor suppressor gene IRF6 is involved in human breast cancer pathogenesis via modulating PI3K-regulatory subunit PIK3R2 expression.?Cancer Management and Research, 2019, 11: 5557-5572.

2.C-F Yang, G-D Yang, T-J Huang et al. EB-virus latent membrane protein 1 potentiates the stemness ofnasopharyngeal carcinoma via preferential activation ofPI3K/AKT pathway by a positive feedback loop. Oncogene, 2016, 35(26): 3419-3431.

3.Q-Q Chu, H-B Huang, T-J Huang et al.?Extracellular serglycin upregulates the CD44 receptorin an autocrine manner to maintain self-renewal innasopharyngeal carcinoma cells by reciprocally?activating the MAPK/β-catenin axis. Cell Death and Disease, 2016, 7: e2456.

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D. Research support

Ongoing projects (RMB)

Shenzhen Science and Technology Innovations Committee（grant no. JC201105170709A）2012-2013 ? ? ? ? ? ? ? ? ? ? ? ? ? ?

PI：Tiejun Huang ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ￥80000

Shenzhen Science and Technology Innovations Committee（grant no. JCYJ20150330102720115）2015-2017

PI：Tiejun Huang? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ?￥150000