RESEARCH INTERESTS

The molecular genetic basis for rheumatoid arthritis; rational development of anti-rheumatic therapy

Autoimmune disease

Cancers of the lymphoid tissues 

GRANTS

 PEER-REVIEWED PUBLICATIONS (in chronological order)

1. Sen M, Cheng Y-H, Goldring MB, Lotz MK, Carson DA. WISP3-dependent regulation of type II collagen and aggrecan production in chondrocytes. Arthritis Rheum 50:488-497, 2004.

2. Lu D, Zhao Y, Tawatao R, Cottam HB, Sen M, Leoni LM, Kipps TJ, Corr M, Carson DA. Activation of the Wnt signaling pathway in chronic lymphocytic leukemia. Proc Natl Acad Sci USA 101:3118-3123, 2004.

3. Hedvat M, Jain A, Carson DA, Leoni LM, Huang G, Holden S, Lu D, Corr M, Fox W, Agus DB. Inhibition of HER-kinase activation prevents ERK-mediated degradation of PPARγ. Cancer Cell 5:565-574, 2004.

4. Loughlin J, Dowling B, Chapman K, Marcelline L, Mustafa Z, Southam L, Ferreira A, Ciesielski C, Carson DA, Corr M. Functional variants within the secreted frizzled-related protein 3 gene are associated with hip osteoarthritis in females. Proc Natl Acad Sci USA 101:9757-9762, 2004.

5. Wu CCN, Lee J, Raz E, Corr M, Carson DA. ecessity of oligonucleotide aggregation for Toll-like receptor 9 activation. J Biol Chem 279:33071-33078, 2004.