Colleges and disciplines to be linked to the Internet: Department of Medicine - Basic Medical College ? ? ? ? ? ?

Name: Li Haiying ? ? ? ? ? ?

Setting: Shenzhen University General Hospital ? ? ? ? ? ?

Major: Cardiovascular Medicine ? ? ? ? ? ?

Title: Professor

Introduction: Li Haiying serves as the Director of the Department of Cardiovascular Medicine at Shenzhen University General Hospital, as a Discipline Leader, Chief Physician, Postgraduate Supervisor, and Doctor. He is a well-known pacing electrophysiologist in China. He studied at the St. Thomas’s Hospital in the UK and at the St. George Electrophysiology Center in Germany. He has been engaged in the ablation of complex arrhythmias and pacemaker therapy for >20 years, and has carried out ablations of atrial fibrillation. He is one of only a few physicians in China who can independently carry out ablation of high-difficulty organic ventricular tachycardia combined with an internal and external membrane. In the field of pacing, His-bundle pacing, left bundle branch pacing, ICD and CRT are complex procedures.

Ly Haiying has undertaken and participated in >10 National Natural Science Foundation and provincial and ministerial level projects. He twice won the third prize of the Provincial And Municipal Science And Technology Progress Award. He has published >10 SCI papers and >20 papers included in the CSCD. He has served as a Member of the Special Committee of Cardiac Arrhythmia of the China Biomedical Engineering office; as a pacemaker and electrophysiological trainer of the Ministry of Health; as a member of the Professional Branch of the Cardiac Pacemaker and Electrophysiology of the Guangdong Medical Association of China Medical Association; as a deputy group leader of the Atrial Fibrillation Group; a Deputy Chairman of the Professional Committee of Cardiac Electrophysiology and Pacing of the Shenzhen Medical Association; and a member of the Standing Committee of the Professional Committee of Cardiovascular Disease of the Shenzhen Medical Association.

Research project:

(1)国家自然科学基金面上项目，81873822，Kisspeptin 介导的MAPK通路在PCOS卵巢功能障碍的调控作用及机制研究，2019/01-2022/12，在研，参加

(2)深圳大学总医院科技人才助推项目，通过循环纤维细胞及HDAC/MCP-1信号途径调节房颤基质纤维化的研究，2018/01-2019/12，在研，主持

(3)深圳市科创委基础研究（自由探索）项目，JCY20170818100355168，运动通过卵巢kisspeptin/GPR54系统改善肥胖所致大鼠生殖功能失调的机制研究，2018/01-2019/12，在研，参加

(4)浙江省自然科学基金一般项目，LY17H040009，肥胖通过卵巢kisspeptin/GPR54系统对卵泡发育和排卵的调控及机制研究，2017/01-2019/12，已结题，参加

(5)温州市科技局重大科技专项项目，ZS2017010，心房颤动及其并发症临床防治新技术的推广研究，2017/01-2019/12，已结题，参加

(6)浙江省科技厅省级公益技术应用研究计划项目，2016C37132，包载雌二醇的肝素-泊洛沙姆温控型水凝胶对Asherman综合征的防治作用及其机制研究，2016/01-2018/12，已结题，参加

(7)浙江省自然科学基金一般项目，LY14H020007，肝细胞“内质网应激-急性期反应”在心肌缺血/再灌注损伤的作用机制研究，2014/01-2016/12，已结题，主持

(8)教育部博士学科点专项科研基金新教师类联合资助课题，20113321120004，生命早期免疫应激对雌鼠卵巢功能长期影响机制的研究，2012/01-2014/12，已结题，参加

(9)温州市科技计划国际合作项目，2010H0063，大豆异黄酮对糖尿病血管内皮功能的影响及机制研究，2010/07-2013/06，8万元，已结题，主持

(10)浙江省卫生厅科技项目，2010KYB072，蛋白激酶介导金属蛋白酶在血管再狭窄中机制实验研究，2010/01-2012/12，0.5万元，已结题，主持

Representative publications:

(1)?Li HY(#), Wu XL, Xiao FY, Zhou XD, Chen Y, Huang WJ(*). Successful percutaneous retrieval of a 33-mm Watchman left atrial appendage occlusion device from the left atrium. JACC Cardiovasc Interv, 2018;11(8):e65-e67.

(2)?Li Hai-Ying(#), Geng Jun-Wei, Yu Han, Tang Xiao-Wen, Yang Xiang-Jun(*), Xue Ling(*), Mitochondrial tRNAThr 15909A>G mutation associated with hypertension in a Chinese Han pedigree, Biochemical and Biophysical Research Communications, 2018.1.1, 495(1): 574~581.

(3)?Li Hai-Ying(#), Dai Zhen-Yu, Wang Bin-Qiao, Huang Wei-Jian(*), A case report of eosinophilic myocarditis and a review of the relevant literature , BMC Cardiovascular Disorders, 2015, 15(1): 1~8.

(4)?Fang Dan-Hong(#), Huang Wei-Jian, Li Hai-Ying(*), Four years follow-up of?epicardial left ventricular pacing by mini-thoracotomy for cardiac?resynchronisation therapy in congestive heart failure (four cases)., Kardiologia Polska, 2015, 73(3): 188~193.

(5)?Zhou Mi(#), Xue Ling, Chen Ya-Ru, Li Hai-Ying, He Qiu-Fen, Wang Bi-Bin, Meng Fei-Long, Wang Meng, Guan Min-Xin(*)?, A hypertension-associated mitochondrial DNA mutation introduces an m(1)G37 modification into tRNA(Met), altering its structure and function, The Journal of Biological Chemistry, 2018.1.26, 293(4): 1425~1438.

(6)?Dong, F. , Li, B. , Jin, X. , Li, X. , Li, Hai-Ying(*), (2019). New cu(ll)-bearing coordination polymer: crystal structure, molecular docking, and protective activity on coronary heart disease by reducing ROS production.?Journal of Theoretical and Computational Chemistry,?18(07), e0217203-4667.

(7)?Xiaozheng Li, Xiaowan Jin, Baoyi Li, Fengquan Dong, Haiying Li(*). (2019). A new mixed-Ligand coordination polymer: crystal structure, molecular docking and alleviating effect on myocarditis by inhibiting the NLRP3-caspase-1 pathway in cardiomyocytes.?ChemistrySelect,?4(39), 11500-11505.

Academic awards:

? (1)李海鹰(2/6)，应激对生殖功能和交感肾上腺功能影响的系列研究, 温州市人民政府办公室，温州市科学技术进步奖，三等奖，2016

? ?(吴雪清，李海鹰，邵蓓，黄欢捷，林源绍，李晓峰)

? (2)李海鹰(3/9)，早期肥胖对雌鼠生殖功能的长期程序化作用，浙江省卫生和计划生育委员会，浙江省医药卫生科技奖，三等奖，2016

? (吴雪清，郑飞云，李海鹰，林源绍，王秀娣，包影，林凤，周强勇，陈海燕)

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