On March 8, 2024, the Lihu Campus of Shenzhen University was delighted to host Professor Wang Yiguo from the School of Life Sciences of Tsinghua University, who gave the 100th guest lecture for the Shenzhen University Medicine Forum on "Hormones in Health and Diseases". Professor Wang Yiguo was invited by Professor Liu Baohua.

In his talk, Professor Wang Yiguo introduced us to the discovery, origins, and functions of various hormones, and the research in this area that has been awarded a Nobel Prize. He then focused on particular examples, including the hormones involved in diabetes. Here, Professor Wang Yiguo discussed the sharp increase in the number of diabetic patients because of diverse, modern lifestyles, disordered work and rest patterns, and the prevalence of a high-sugar diet. He then outlined the history and function of insulin and other hormones used to treat diabetes. During his vivid talk, Professor Wang Yiguo explained the experimental process that led to the discovery of the Asprosin, Famsin, Feimin and Cholesin genes that encode four hormones involved in glycolipid metabolism. Alongside, we gained insight into the thinking, methods and spirit of unity and cooperation of Professor Wang Yiguo's research team. After his talk, Professor Wang Yiguo actively interacted with the audience, patiently answered various questions raised by teachers and classmates, and engaged in a heated discussion on the interaction between intestinal flora and intestinal hormones. Here, he discussed the new "diet drug" based on GLP-1, and called on everyone to lose weight rationally rather than using pharmaceutical products for weight loss due to potent issues with drug dependence and potential harm.

Brief introduction to the speaker

Wang Yiguo, Professor of School of Life Sciences, Tsinghua University, Researcher and PhD supervisor of Tsinghua University-Peking University Joint Center for Life Sciences. Winner of National Outstanding Youth Fund, Chief Scientist of National Key R&D Program of Ministry of Science and Technology, and national-level talent. His research is devoted to understanding the hormone regulation of glucose and lipid metabolism. He has identified and named several hormones regulating glucose and lipid metabolism, including Famsin, Feimin and Cholesin, and published his findings in elite, international journals such as Cell, Nature, Cell Metabolism and Cell Research. He has undertaken and participated in many projects, including those of the Basic Science Center of the National Natural Science Foundation of China, the Outstanding Youth Fund, innovative groups and key projects, and the key R&D plan of the Ministry of Science and Technology. He is currently an editorial board member for Life Metabolism, a supervisor for the China Biophysics Society, and Vice President of the Metabolism Branch of the China Cell Biology Society.