NAME: Lu, Minhua, Tracy

POSITION TITLE: Professor of Biomedical Engineering, Shenzhen University School of Medicine; Executive Deputy Director, Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging

EDUCATION/TRAINING

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A.?? Personal Statement

My research interests are mainly in the biomedical ultrasound imaging and instrumentations, biomechanical modeling of soft tissues, ultrasound elasticity imaging and measurement. Research in my lab has been continuously supported by the National Natural Science Foundation in China (NSFC) and the Shenzhen government and Guangdong Province. I am the Executive Deputy Director of Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, China, and have received >20 grants as the principle investigator over the course of my career. I was awarded the 1^st Basic Science Foundation for Distinguished Young Scholars of Shenzhen Government in 2010, and several best paper awards. I serve as a reviewer for several international journals, including Ultrasound in Medicine and Biology, IEEE Transactions of Biomedical Engineering, and Ultrasonics, and am also a reviewer for the National Natural Science Foundation of China (NSFC), Medical Science Division and Information Science Division. I have published >60 peer-reviewed technical papers, hold one US patent and three Chinese patents.

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B.?? Positions and Honors

Positions and Employment

07/2001–06/2002??????? Software Engineer, Global Technique and Engineering Center (GTEC) of Microsoft, Shanghai, China

09/2007 – 12/2010????? ?????? Assistant Professor, Department of Biomedical Engineering, School of Medicine, Shenzhen University

Director, Medical Imaging Research Center

12/2010 – 12/2016????? Associate Professor, Department of Biomedical Engineering, School of Medicine, Shenzhen University

12/2016 – present?????? ?????? Professor, School of Biomedical Engineering, Shenzhen University

Executive Deputy Director, Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging

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Awards and Honors

2016??????????????? Best Poster Award, The 47^th Annual Congress of Korean Society of Ultrasound in Medicine, Seoul, Korea,

2015?????? ????????????? Best paper award (3^rd Prize), Annual Conference on Biomedical Engineering of China

2011?????? ????????????? Best paper award (1^st Prize), Annual Conference on Biomedical Engineering of China

2010???????????? ???? Distinguished Young Talent, Shenzhen Government

2009?????? ????????????? Shenzhen Young Investigator, Shenzhen Government

2008?????????? ? President Award for Outstanding Research Performance/Achievements, Shenzhen University

2007????????? ??? Distinguished PhD Thesis Award, The Hong Kong Polytechnic University

2002-2006 ?? Predoctoral Fellowship from the University Grants Committee (UGC), Hong? Kong

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Professional Service and Memberships

Secretary-General, Instrument Engineering Development Committee, Chinese Association of Ultrasound in Medicine and Engineering (2012/09~)

Standing Committee, Chinese Association of Ultrasound in Medicine and Engineering (2016/09~)

Member of IEEE: Institute of Electrical and Electronic Engineers Inc; (2005/09~)

EMBS: Biomedical Engineering Society

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C.?? Publications and Patents

?(*: corresponding/co-corresponding author)

BOOK CHAPTER

1.??????? Yi Zheng, Xin Chen, Aiping Yao, Haoming Lin, Yuanyuan Shen, Ying Zhu, Minhua Lu, Tianfu Wang and Siping Chen. Shear Wave Propagation in Soft Tissue and Ultrasound Vibrometry. In: Wave Propagation Theories and Applications, InTech, ISBN 978-953-51-0979-2, pp 1-24, Feb 2013.

2.??????? LU MH and Chen SP. Physics of ultrasound. In: Foundations of Medical Ultrasound, People’s Military Medical Press, ISBN 978-7-5091-3137-4, p1-43, 2009. (in Chinese)

3.??????? LU MH. Bioeffects of ultrasound. In: Foundations of Medical Ultrasound, People’s Military Medical Press, ISBN 978-7-5091-3137-4, p44-50, 2009. (in Chinese)

4.??????? Lu MH, Zheng YP, and Huang QH. Ultrasound elastomicroscopy using water beam indentation: preliminary study. In: State of the Art: Ultrasonics in Medicine (International Congress Series 1274), Elsevier, ISBN 0-444-51640-9. p87-96, 2004

PEER-REVIEWED JOURNAL PAPERS (Selected)

1.????? Lu MH, Huang S, Yang XL, Yang L and Mao R. Semianalytical Solution for the Deformation of an Elastic Layer Under an Axisymmetrically Distributed Power-Form Load: Application to Fluid-Jet-Induced Indentation of Biological Soft Tissues, BioMed Research International, 9842037, 1-10, March 2017.

2.????? Mao R, Zhang PH, Li XL, Liu X, Lu MH*. Pivot selection for metric-space indexing, International Journal of Machine Learning and Cybernetics, 7(2): 311-323, Apr 2016.

3.????? Min Guo, Derek Abbott, Minhua Lu*, Huafeng Liu. Quasi-plane shear wave propagation induced by acoustic radiation force with a focal line region: a simulation study, Australasian Physical & Engineering Sciences In Medicine, 39(1): 187-197, Mar 2016

4.????? Jun Shi, Shichong Zhou, Xiao Liu, Qi Zhang, Minhua Lu*, TianfuWang. Stacked deep polynomial network based representation learning for tumor classification with small ultrasound image dataset, Neurocomputing, 194: 87-94, June 19 2016.

5.????? Zhifan Gao, William Kongto Hau, Minhua Lu, Wenhua Huang, Heye Zhang, Xin Liu. An Automated Framework for Detecting Lumen and Media–Adventitia Borders in Intravascular Ultrasound Images, Ultrasound in Medicine and Biology, 41(7):2001-2021, 2015.

6.????? Rui Mao, Honglong Xu, Wenbo Wu, Jianqiang Li, Yan Li, and Minhua Lu*. Overcoming the Challenge of Variety: Big Data Abstraction, the Next Evolution of Data Management for AAL Communication Systems. IEEE Communications Magazine, 53 (1), 42-47, Jan 2015.

7.????? Jun Shi, Qikun Jiang, Rui Mao, Minhua Lu*, Tianfu Wang. FR-KECA: Fuzzy Robust Kernel Entropy Component Analysis. Neurocomputing , 149: 1415-1423, 2015.

8.????? Huahua Xiong, Xin Liu, Xiaohong Tian, Lina Pu, Heye Zhang*, Minhua Lu, Wenhua Huang and Yuan-Ting Zhang. A numerical study of the effect of varied blood pressure on the stability of carotid atherosclerotic plaque. BioMedical Engineering OnLine, 2014, 152.

9.????? Minhua Lu, Dan Wu, Wanhua Lin, Heye Zhang and Wenhua Huang. A Stochastic Filtering approach to Recover Strain Images from Quasi-static Ultrasound Elastography. BioMedical Engineering OnLine, Feb 2014, 13: 15-31.

10.?? Minhua Lu, Heye Zhang, Jun Wang, Jinwei Yuan, Zhenghui Hu and Huafeng Liu. Reconstruction of Elasticity: A Stochastic Model-based Approach in Ultrasound Elastography. BioMedical Engineering OnLine, Sep 2013, 12: 79- 97.

11.?? Zhenghui Hu, Heye Zhang, Jinwei Yuan, Minhua Lu*, Siping Chen and Huafeng Liu. An H∞ Strategy for Strain Estimation in Ultrasound Elastography Using Biomechanical Modeling Constraint. PLoS One, 8(9): e73093, Sep 2013.

12.?? Min-Hua Lu*, Rui Mao, Yin Lu, Zheng Liu, Ruichao Sun, Tian-fu Wang, Si-Ping Chen. Quantitative Imaging of Young’s Modulus of Soft Tissues from Ultrasound Water Jet Indentation: A Finite Element Study. Computational and Mathematical Methods in Medicine, 2012: 97487.

13.?? Lu MH, Zheng YP, Lu HB, Huang QH, and Qin L. Evaluation of bone-tendon junction healing using water jet ultrasound indentation method. Ultrasound in Medicine and Biology. 35(11): 1783-1793, 2009.

14.?? Lu MH, Zheng YP, Yu W, Huang QH, Huang YP. A hand-held indentation system for the assessment of mechanical properties of soft tissues in vivo. IEEE Transactions on Instrumentation and Measurement. 58(9): 3079-3085, 2009.

15.?? Lu MH, Zheng YP, Huang QH, Ling C, Wang Q, Bridal L, Qin L, Mak A. Noncontact Evaluation of Articular Cartilage Degeneration Using a Novel Ultrasound Water Jet Indentation System. Annals of Biomedical Engineering. 37(1):?164-175, 2009.

16.?? Lu MH, Zheng YP, and Huang QH. A novel method to obtain modulus image of soft tissues using ultrasound water jet indentation. IEEE Transactions on Biomedical Engineering. 54(1): 114-121, 2007.

17.?? Lu MH, Zheng YP, and Huang QH. A Novel non-contact ultrasound indentation system for measurement of tissue material properties using water compression. Ultrasound in Medicine and Biology. 31: 817-826, 2005.

?PATENT

1.????? Zheng YP and Lu MH, Noncontact measurement of material properties. United States patent issued. No. 7,124,636, Oct 24 2006.

2.????? Lu MH, Sun RC, Wang TF and Chen SP. A real time displacement estimation method for ultrasound elastography. Chinese Patent (issued), No. 201210561235.9, 2012.

3.????? Mao R, Lu MH, Liu G. Distributed metric-space indexing system, Chinese patent issued. No. 2013SR047975, May 21 2013.

4.????? Mao R, Lu MH, Zhang D. MSIndex - An inverted indexing system, Chinese patent issued. No. 2013SR047697, May 21 2013.

5.????? Liu GQ, Lu MH, Xia H, Li SQ, Li YH, Xia ZW, Wang S and Huang X. System and imaging method for magno-acoustic imaging. Chinese Patent (filed), No. 201210393077.0, 2012.

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D.?? Research Support (selected)

1.?Quantitative Evaluation of Female Pelvic Floor Dysfunction Using Ultrasound RF Signals,Normal Project, National Natural Science Foundation of China (NSFC), China (61471243; 2015-2018, RMB 850 k)?PI: Lu MH

2.?Targeting asymptomatic Sudden Death: Feature Extraction and Data Assimilation Techniques,Major Project for Basic Science, Shenzhen Bureau of Science Technology and Information, Shenzhen, China (JCYJ20150731160834611; 2015-2018, RMB 3,000k)?PI: Lu MH

3.?High-Speed, Broad-View Ultrasound Imaging Equipment for Arterial Structural Dynamics Monitoring?Shenzhen-Hongkong Joint Project, Shenzhen, China (SGLH20131010163759789; 2014-2017, RMB 1,500k) PI: Lu MH

4.?Advanced Ultrasound Evaluation of Vulnerable Plaque in Artery?Distinguished Youth Talents Fund, Shenzhen Bureau of Science Technology and Information, Shenzhen, China (JC201006020025A; 2011-2013, RMB 1,000k)PI: Lu MH

5.?Noncontact Ultrasound Evaluation of Early Degeneration of Articular Cartilage Using Mechanical and Acoustical Parameters?Youth Fund, National Natural Science Foundation of China (NSFC), China (60901015; 2010-2012, RMB 240k)PI: Lu MH

6.?A High Resolution Elasticity Arthroscopy for Assessment of Early Degeneration of Articular CartilageBasic Science Research Fund, Shenzhen Bureau of Science Technology and Information, Shenzhen, China (JC200903120032A; 2009-2012, RMB 200k)PI: Lu MH

7.?A Rapid Ultrasound Elastography Algorithm and System?Innovative Technology Fund, Shezhen Bureau of Science Technology and Information, Shenzhen, China (SY200806270121A; 2009-2011, RMB 300k)PI: Lu MH

8.?Encoded-ultrasound Vibro-Acoustography and its Application?Key Project, National Natural Science Foundation of China (NSFC), China (61031003; 20111-2014, RMB 2,600k)PI: Chen SP

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Contact

Email:luminhua@szu.edu.cn

Office Tel:0755-86671915